Happily Ever After

Archive for February 2008

Out of my 12 eggs retrieved 8 were mature (little disappointing but oh well) The good news is out of the 8 that were ICSI’d all 8 fertilized! I don’t have any grades since I’m only 1 day past ER today. Tomorrow I guess they will have grades. I won’t know till I go in for transfer though. What sucks is my RE won’t even consider doing anything but a 2dt. I guess that is for the best but it would still be nice to transfer 2 blasts. I have to be at the hospital at 7:30 tomorrow morning. Yet another Saturday of getting up at the crack of dawn. I just hope all are great quality. If they are he will freeze them on day 2. If they are not great quality they will push for day 3 or 5 to freeze. I hope that they ask me before they freeze them. I need to know how much $$ it is. I also want them frozen in batches of 3 if I have 6 to freeze. (since not all embryo’s make the thaw) besides if this IVF doesn’t work I’ll be telling my DH and my RE that I’m transferring 3 on an FET. DH is scared to transfer 3 but at this point I’m willing to take the risk of all 3 taking. I highly doubt that would happen though. Heck I highly doubt all 3 would survive the thaw. Then again I could be wrong. Stranger things have happened.

I’m pretty happy with my results but still nervous/disappointed in doing a 2dt. People that are “young” with lots of embryo’s usually get pushed for a 5dt. However given my history my RE doesn’t want to risk it…I’m almost willing to take the risk. Part of me wants to call and talk to him about the transfer (or one of the embryologists). Needless to say I’ll be asking the embryologist lots of questions before they do the transfer tomorrow.

Looks like the LH did the trick!

12 Eggs retrieved! The next hurdle is finding out how many were mature and how many fertilized (immature eggs they don’t fertilize, they do keep an eye on them and try to mature them in the lab but most of the time they don’t even attempt to fertilize immature eggs) I’ve never had a problem with immature eggs but the most I’ve had retrieved was 7 so we’ll see.

We are doing a 2 day transfer (Saturday at 8 am) either way. In the past my embryo’s have been fine on day 2 (4 cells-which is right where they should be) but by day 3 the cell growth slows down (by day 3 they should be around 8 cells) Mine were almost always only 5 cells on day 3. It’s obvious that my embryo’s don’t like the lab. Either that or they stink. Needless to say my Re is not taking any chances. In the studies they have done they have shown that pushing till day 3 doesn’t increase success rates for them. They almost always do 2 day transfers. I did talk to the embryologist about the fact that the embryo is in the tube till around day 4 but she said the uterus is just as good as an environment as the tube. In fact she says there really is no difference accept for the fact that it floats around in the uterus for a few days.

My RE also wants me on strict bed rest for 3 days (Saturday, Sunday and Monday) that means in a reclining/laying down position. It sounds stupid but they have done studies that show it increases their success/implantation rates. I personally think it’s silly but I’m going to abide by my doctors orders. Jon is adamant that we follow doctors orders. He has done lots of studies and seems to know what he is doing so I have to trust him.

Tomorrow after 10:30 I can call for an update. They tried to explain their grading score but it’s very complicated. They said it goes up to 7 but can go up to 12 (higher the number better the quality) regardless they said there will be an embryologist there for my transfer along with my RE to answer any and all of my questions. They do their grading based on how the cells divide. Essentially, they have found, that cells that divide evenly (meaning the cells are the same size, not some small and some large) have high implantation rates regardless of what day they are transferred (they have done studies where they number the embryo’s on day 1/2 and follow them through day 5 to prove the theory. They also look to see how many nucleus is in each cell. Each cell is only supposed to have 1 nucleus but in some cases each cell will have more then 1. Again, their studies have shown that even cells with 1 nucleus have better implantation rates.

Ok off to rest now. I’m supposed to be resting today.

I had to do my HCG shot (10,000 units) in the butt last night. I used the IM needle (25G 1 1/2″) I couldn’t possibly get the needle in all the way. I tried but at one point it hurt. I think I got it 1/2 to 3/4 of the way in. My nurse said I should be fine. She also said I had to have someone help me with the PIO shots because the needle has got to go in all the way.

SO someone that has a butt twice as large as mine has to use the same size needle? Where on earth is the logic in that? How can I be sure that the 1 1/2″ needle is the right size?

My husband HATES needles but said he’d do it. Lovely, bend over honey it’s time.

Why on earth is having a baby this hard? It’s supposed to be easy. And my kid sure as heck will know what I went through to conceive him or her. I’ve about HAD it with these shots. Just as my belly feel better my butt is sore. I don’t think I’m going to be able to sit if the PIO shots hurt as much as the HCG shot did. I’m still sore today but that could be because it’s an HCG shot.

I sure as heck hope I didn’t mess up my HCG shot. All the other IVF’s have been in my belly so I should be fine right?

emotions

Posted on: February 26, 2008

My emotions are all over the place. I went from being excited to not wanting to do this again. I often find myself looking over at the pregnancy boards on FF. I don’t know why I do it to myself. To be perfectly honest I get jealous of the woman over there. Especially those that do IVF and get pregnant right away, and some of them with twins. How someone else can be blessed so abundantly but I can’t even get 1 baby and I’ve had 4 embryo’s transfered thus far just doesn’t seem fair. Don’t get me wrong I’m not hoping for any more then 1 baby. I know what is best is having a healthy pregnancy. Anyhow, I really should get off the internet. I’m an emotional wreck. I just want to get the next two weeks over with.

E2=1,539!!!
LH they didn’t measure and I’m VERY nervous!!!
-I’m not on anything to keep me from ovulating…the nurse said they push people this far all the time…Please tell me this is normal..I”m so afraid I’ll surge on my own!

Lining = 11.8 A different tech did it this time so I’m sure that is why it is “thinner” then Saturday. Also no one ever told me it was triple but I looked at the screen Saturday and there was 3 distinct lines so I’m pretty sure it is.

Left: 1@16, 2@15
Right: 1@17, 2@16, 4@15, 2@13

Oh my word I am in SHOCK!!! I feel like I’m going to wake up from a dream soon!!!

I am just over the moon right now! Even if I don’t get a BFP I’ll be so so so so so happy if I get some to freeze!!!

If I do have 12 follies My E2 should be around 2,400 at trigger right? shouldn’t it be around 200+ per mature follicle?

My next u/s and b/w is tomorrow!

I can’t even believe this is happening…I almost feel fertile.

I had called & the nurse wasn’t totally sure of my instructions so she read what she saw:

same dosages: 150 Gonal F, 2 vials of Repronex (300iu FSH & 150iu LH)

Ok so if LH makes me surge what on earth is stopping me if I’m pumping my body full of LH?

Update:

Re changed his mind. I take my meds tonight along with cetrotide. I trigger tomorrow but not sure what time yet. They said retrievals are in the mornings…so some time very early Thursday morning.

I’m so nervous that my E2 is to low. I’m sure it will go up between today and tomorrow…no more b/w or ultrasounds. 😦

I’m so nervous…this is going to smoothly…something’s got to go wrong somewhere along the way right?

Nausea

Posted on: February 24, 2008

I’ve had Nausea since late last week. At first I thought I was coming down with the stomach bug that swept through work last month. However today I read the side effects of Repronex and nausea is one of them. I don’t know how many more days I can take this. I’m going to mention it to the nurse on Monday. If my follies are still smallish I’m going to see if there is anything they can give me that will help with nausea. I think I’ll only be stiming a few more days so in reality I won’t have to deal with this much longer. This is the last time though that I will use Repronex. If I have to do another IVF I will request another form of LH.

U/s this morning showed:
R: 4@11mm, 1@12mm
L: 2@10mm
Lining 12.4 triple layer!

My b/w came back:

E2 833
LH 1.3
TSH I will get back in a few days.

Instructions: increase dosage: 150 Gonal F, 2 vial Repronex (total FSH=300iu total LH =150iu)

Originally they were having me go in on Tuesday for my b/w and u/s (that would be after 9 days of stims) but I called my RE later and told him I was nervous so he is bringing me in on Monday.

I HATE the Repronex…It stinks and gives me HUGE sore red welts on my belly. 😦 Not to mention they give me HUGE red welts and it BURNS! If I inject it slowly it doesn’t hurt to much. The nurse also said to let it sit out for 15 minutes and that should minimize the red welting. I’m up to 3 shots a day now.

I asked my RE and he said they freeze embryo’s on day 1, 3 or 5. What day they freeze them depends on the embryo quality I guess. of course I don’t expect to have any to freeze but oh man would it be nice to do FET’s if this IVF doesn’t work!

I’m trying not to count my chickens before they hatch but I really think I’ll stim for at least 9-10 days this time!! And I’m so excited he increased my dosage. Here is what I think (and I could be way off base here)

either my body is getting used to the drugs OR the increase in dosage has helped recruit more follies, vs keeping me at the same dosage (which my last RE always did-or lowered it) and having the already growing follies suck up all the FSH and continue to grow.

not sure if that makes sense but I really think the steady increase of meds is helping to recruit more. Either that or my body likes the repronex. I hate the welts though!!

This was a very quick update because DH is waiting for me to finish a movie with him. 🙂